Archive for Alzheimer’s

september 2015: 1

Building Muscle
“Lab-grown muscle fibers offer new muscular dystrophy model”
Future applications include other degenerative muscle diseases.
Harvard Medical School News — August 3, 2015

Fat in the Family?
Study could lead to therapeutics that boost metabolism
Harvard Medical School News — August 20, 2015

UGA’s Regenerative Bioscience Center collaborates in development of brain-friendly interfaces
“…proof of concept that extracellular matrix can be used to ensheathe a functioning electrode without the use of any other foreign or synthetic materials…. the extracellular matrix derived electrodes adapted to the mechanical properties of brain tissue and were capable of acquiring neural recordings from the brain cortex.”
Regenerative Bioscience Center, University of Georgia — August 5, 2015

We transformed living cells into tiny lasers
Harvard Medical School Dermatology/The Conversation, American pilot, July 27, 2015

Alzheimer’s research

Immune mechanisms of synapse loss in health and disease (YouTube lecture)
Beth Stevens, Broad Institute/Boston Children’s Hospital —  July 8, 2015
Her lab is “using a combination of live imaging, molecular, biochemical, and neuroanatomical approaches to investigate the molecular mechanisms by which immune molecules and immune cells called microglia prune synapses in health and disease. Her recent work demonstrates [how] immune-related pruning pathways mediate aberrant synapse loss and dysfunction in neurodegenerative diseases (e.g., Alzheimer’s and Huntington’s disease) and neurodevelopmental disorders, including autism.

Iron-containing inflammatory cells seen in Alzheimer’s brains
“Using high-field MRI technology and staining techniques, scientists have located inflamed, iron-containing scavenger cells in a memory-formation structure in the brains of Alzheimer’s patients who died”
Stanford Medicine News Center — July 20, 2015

something completely different

Why the long face? Horses and humans share facial expressions
“Horses and humans share surprisingly similar facial expressions”
University of Sussex — August 5, 2015



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may 2015

Today’s posting: courtesy of Harvard University researchers and science writers

Activating genes on demand
Wyss Institute for Biologically Inspired Engineering at Harvard University — March 3, 2015

Blood Work
“Decreased red blood cell clearance appears to predict serious disease”
Harvard Medical School News — April 28, 2015

How to Kill a Protein
“Cells have been doing it for millions of years, and we’re just starting to learn their tactics”
Harvard Medical School News — April 22, 2015
“Artificially activating a neural link in mice can reduce eating without chronic hunger”
Harvard Medical School News — April 28, 2015
New Chapter in Epigenetics
“Unsuspected DNA modification raises possibility of new carrier of heritable epigenetic information”
Harvard Medical School News — April 30, 2015
‘New clarity’ against Alzheimer’s
“Recent findings open the door for a breakthrough, Tanzi says”
Harvard Gazette, Science and Health/Health and Medicine — May 5, 2015

Zooming in on Transcription
“How RNA machinery navigates our genomic obstacle course”
Harvard Medical School News — April 23, 2015

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april 2015:1

Experimental cancer drug restores memory in mouse model of Alzheimer’s
Yale University News — March 31, 2015

Human Brains Age Less than Previously Thought
Biotechnology and Biological Sciences Research Council (BBSRC) — March 5, 2015

Innovative light therapy reaches deep tumors
Washington University School of Medicine — March 9, 2015

Seeing the Light
“Gene therapy slows vision loss in mouse models of retinal degeneration”
Harvard University School of Medicine — March 23, 2015

Skin Tough
“Study at Berkeley Lab’s Advanced Light Source Shows Why Skin is Resistant to Tearing”
Lawrence Berkeley National Laboratory — March 31, 2015

Synaptic Shortcut
“Newly discovered brain pathway overturns anatomy, could solve antipsychotic mystery”
Harvard University School of Medicine — March 6, 2015

Transport molecule forms a protective structure to guide proteins to cell membrane
University of Chicago Medicine — March 5, 2015


Metabolic Path to Improved Biofuel Production
Lawrence Berkeley National Laboratory — March 4, 2015

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march 2015

A new stem cell advance
“Scientists produce hypothalamic neurons, which can help target a range of conditions by using lab dishes”
Hannah Robbins, Harvard Gazette Science and Health — March 2, 2015

A new understanding of Alzheimer’s
“…mitochondria — cellular power plants — might be at the center of the disease”
Peter Reuell, Harvard Gazette Science and Health — February 25, 2015

Brain Waves
“Basal forebrain neurons fine-tune consciousness by synchronizing rhythms in the cortex”
Jake Miller, Harvard Medical News — March 2, 2015

Perception of food consumption overrides reality
“Research suggests anti-aging benefits of calorie restriction without the restriction”
Karen Feldscher, Harvard School of Public Health Communications — February 26, 2015

background: proteins

Strike a Pose
“The structure of our proteins informs how we function”
Stephanie Dutchen, Assembled with care, Harvard Medical School–Winter 2015


Bionic Leaf
“Researchers use bacteria to convert solar energy into liquid fuel”
Elizabeth Cooney, Harvard Medical news — February 9, 2015

A trap for greenhouse gas
“Microcapsule method offers new approach to carbon capture and storage at power plants”
Harvard University and Lawrence Livermore National Laboratory — February 5, 2015

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October 2014: 4

‘Alzheimer’s in a Dish’
“3-D culture system replicates disease, confirms amyloid hypothesis”
Sue McGreevey, Harvard Medical News — October 14, 2014

Basel biomedical bring cells into the fast lane
“…novel insights into the regulation of directional cell migration”
University of Basel — October 6, 2014

Drug-infused nanoparticle is right for sore eyes
Pamela Smyth, University of Waterloo News — October 8, 2014

New Discovery in Regulating Autoimmune Diseases
“A natural molecule delays disease onset and reverses disease progression”
Marjorie Montemayor-Quellenberg, Harvard Medical News — October 14, 2014

Scientific breakthrough will help design the antibiotics of the future
Bristol University News — October 17, 2014

Solid nanoparticles can deform like a liquid
“Unexpected finding shows tiny particles keep their internal crystal structure while flexing like droplets”
David L. Chandler, MIT News Office — October 12, 2014


Are We Really Conscious?
Michael Graziano — Sunday Review, New York Times — October 10, 2014

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August 2014: 3

Study finds coronary arteries hold heart-regenerating cells
Leigh MacMillan, ResearchNews@Vanderbilt, Vanderbilt University Medical Center — Aug. 20, 2014

The channel that relaxes DNA
“Relaxing DNA strands using nano-channels: instructions for use
SISSA International School for Advanced Studies, Trieste — August 19, 2014

“Trojan horse” treatment could beat brain tumours
“A smart technology which involves smuggling gold nanoparticles into brain cancer cells has proven highly effective in lab-based tests”
University of Cambridge Research News — August 13, 2014

Zipper Triggers Bacterial Invasion
“Freiburg researchers discover new strategy germs use to invade cells”
University of Freiburg, Newsroom 2014 — August 8, 2014

One in three cases of Alzheimer’s worldwide potentially preventable, new estimate suggests
University of Cambridge Research News — July 14, 2014


Origami robot folds itself up, crawls away
“Prototype made almost entirely of printable parts demonstrates crucial capabilities of reconfigurable robots”
Larry Hardesty, MIT News Office — August 7, 2014

Completely off topic

Feeling bad at work can be a good thing
University of Liverpool, University News — August 20, 2014

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July 2014: 3

Protein’s “hands” enable bacteria to establish infection, research finds
Kansas State University, News and Communications —  July 15, 2014

Managing Ecosystems Via Genomics
“New genome editing tool offers strategy to manage insect-borne disease”
Kristen Kusek, Harvard Medical News — July 17, 2014

Study shows epigenetic changes can drive cancer
Dipali Pathak, News Office, Baylor College of Medicine — July 25, 2014

New drug target can break down cancer’s barrier against treatment
Cancer Research UK, press release — July 27, 2014

Scientists Discover New Mechanism of Drug Resistance
“Microorganisms can evade treatment through temporary changes”
Marla Vacek Broadfoot, Office of News and Communication, Duke University — July 27, 2014

 BU Researchers Discover that Klotho is Neuroprotective Against Alzheimer’s Disease Toxic Amyloid
Boston University Medical Center, Health & Medicine, News Releases — July 28, 2014


Penn Study: Understanding Graphene’s Electrical Properties on an Atomic Level
Evan Lerner, Penn News, University of Pennsylvania — July 15, 2014

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